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Title: The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67)      
description:
Glutamate decarboxylase 1 (E.C.4.1.1.15)
privacy:
not applicable
aggregation:
instance of dataset
ID:
PDB:2OKJ
refinement:
curated
keywords:
LYASE
PLP-dependent decarboxylase
creators:
Fenalti, G.
Law, R.H.P.
Buckle, A.M.
Langendorf, C.
Tuck, K.
Rosado, C.J.
Faux, N.G.
Mahmood, K.
Hampe, C.S.
Banga, J.P.
Wilce, M.
Schmidberger, J.
Rossjohn, J.
El-Kabbani, O.
Pike, R.N.
Smith, A.I.
Mackay, I.R.
Rowley, M.J.
Whisstock, J.C.
availability:
available
types:
structure
strain:
YRD-15
name:
Homo sapiens
ID:
ncbitax:9606
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
authors:
Fenalti, G.
Law, R.H.P.
Buckle, A.M.
Langendorf, C.
Tuck, K.
Rosado, C.J.
Faux, N.G.
Mahmood, K.
Hampe, C.S.
Banga, J.P.
Wilce, M.
Schmidberger, J.
Rossjohn, J.
El-Kabbani, O.
Pike, R.N.
Smith, A.I.
Mackay, I.R.
Rowley, M.J.
Whisstock, J.C.
alternateID:
doi:10.1038/nsmb1228
year:
2007
ID: pmid:17384644
title:
GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
formula:
C4 H9 N O3
name:
THREONINE
roles:
chemical component
formula:
C4 H7 N O4
name:
ASPARTIC ACID
roles:
chemical component
formula:
C9 H11 N O2
name:
PHENYLALANINE
roles:
chemical component
formula:
C3 H7 N O3
name:
SERINE
roles:
chemical component
formula:
C4 H8 N2 O3
name:
ASPARAGINE
roles:
chemical component
formula:
C6 H13 N O2
name:
LEUCINE
roles:
chemical component
formula:
C3 H7 N O2
name:
ALANINE
roles:
chemical component
formula:
C6 H15 N4 O2 1
name:
ARGININE
roles:
chemical component
formula:
C5 H9 N O2
name:
PROLINE
roles:
chemical component
formula:
C6 H15 N2 O2 1
name:
LYSINE
roles:
chemical component
formula:
C2 H5 N O2
name:
GLYCINE
roles:
chemical component
formula:
C5 H9 N O4
name:
GLUTAMIC ACID
roles:
chemical component
formula:
C5 H10 N2 O3
name:
GLUTAMINE
roles:
chemical component
formula:
C5 H11 N O2
name:
VALINE
roles:
chemical component
formula:
C6 H13 N O2
name:
ISOLEUCINE
roles:
chemical component
formula:
C9 H11 N O3
name:
TYROSINE
roles:
chemical component
formula:
C6 H10 N3 O2 1
name:
HISTIDINE
roles:
chemical component
formula:
C5 H11 N O2 S
name:
METHIONINE
roles:
chemical component
formula:
C3 H7 N O2 S
name:
CYSTEINE
roles:
chemical component
formula:
C11 H12 N2 O2
name:
TRYPTOPHAN
roles:
chemical component
formula:
C14 H24 N3 O7 P
name:
2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE)
roles:
chemical component
formula:
C4 H9 N O2
name:
GAMMA-AMINO-BUTANOIC ACID
roles:
chemical component
formula:
C12 H19 N2 O7 P
name:
4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID
roles:
chemical component
formula:
H2 O
name:
WATER
roles:
chemical component
name:
GAD1, GAD, GAD67
name:
X-RAY DIFFRACTION
ID:
pdb:2OKJ
ID:
rcsb:RCSB041250
accessURL: https://files.rcsb.org/download/2OKJ.xml.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
PDBML/XML
accessType:
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authentication:
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authorization:
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accessURL: https://files.rcsb.org/download/2OKJ.pdb.gz
storedIn:
Protein Data Bank
qualifier:
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license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
PDB Format
accessType:
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authentication:
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authorization:
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accessURL: https://files.rcsb.org/download/2OKJ.cif.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
PDBx/mmCIF
accessType:
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authentication:
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authorization:
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accessURL: http://www.rcsb.org/pdb/download/downloadFile.do?fileFormat=FASTA&compression=NO&structureId=2OKJ
storedIn:
Protein Data Bank
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
FASTA
accessType:
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authentication:
none
authorization:
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accessURL: https://files.rcsb.org/download/2OKJ-sf.cif.gz
storedIn:
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qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
CIF
accessType:
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authentication:
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authorization:
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accessURL: https://files.rcsb.org/download/2OKJ.pdb1.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
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accessType:
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authentication:
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authorization:
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accessURL: http://www.rcsb.org/pdb/explore/jmol.do?structureId=2OKJ&bionumber=1
storedIn:
Protein Data Bank
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
JSmol
accessType:
view
authentication:
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authorization:
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abbreviation:
wwPDB
homePage: http://www.wwpdb.org
ID:
SCR:006555
name:
Worldwide Protein Data Bank
abbreviation:
PDB
homePage: http://www.rcsb.org/pdb/
ID:
SCR:012820
name:
Protein Data Bank