description: |
Netrin-1
|
privacy: |
not applicable
|
aggregation: |
instance of dataset
|
ID: |
PDB:4OVE
|
refinement: |
curated
|
keywords: |
APOPTOSIS
similar to laminin gamma-1
domain VI: beta-sandwich jelly-roll
domains V-1
V-2
V-3: laminin-type epidermal growth factor
structural calcium
axon guidance cue
survival factor
neogenin
DCC
UNC5A
UNC5B
UNC5C
UNC5D
DSCAM
extracellular matrix
|
creators: |
Grandin, M.
Meier, M.
Delcros, J.G.
Nikodemus, D.
Reuten, R.
Patel, T.R.
Goldschneider, D.
Orriss, G.
Krahn, N.
Boussouar, A.
Abes, R.
Dean, Y.
Neves, D.
Bernet, A.
Depil, S.
Schneiders, F.
Poole, K.
Dante, R.
Koch, M.
Mehlen, P.
Stetefeld, J.
|
availability: |
available
|
types: |
structure
|
name: |
Mus musculus
|
ID: |
ncbitax:10090
|
name: |
Homo sapiens
|
ID: |
ncbitax:9606
|
authors: |
Grandin, M.
Meier, M.
Delcros, J.G.
Nikodemus, D.
Reuten, R.
Patel, T.R.
Goldschneider, D.
Orriss, G.
Krahn, N.
Boussouar, A.
Abes, R.
Dean, Y.
Neves, D.
Bernet, A.
Depil, S.
Schneiders, F.
Poole, K.
Dante, R.
Koch, M.
Mehlen, P.
Stetefeld, J.
|
alternateID: |
doi:10.1016/j.ccell.2016.01.001
|
year: |
2016
|
ID: | pmid:26859457 |
title: |
Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers.
|
formula: |
C3 H7 N O2
|
name: |
ALANINE
|
roles: |
chemical component
|
formula: |
C5 H10 N2 O3
|
name: |
GLUTAMINE
|
roles: |
chemical component
|
formula: |
C5 H9 N O2
|
name: |
PROLINE
|
roles: |
chemical component
|
formula: |
C4 H7 N O4
|
name: |
ASPARTIC ACID
|
roles: |
chemical component
|
formula: |
C3 H7 N O2 S
|
name: |
CYSTEINE
|
roles: |
chemical component
|
formula: |
C3 H7 N O3
|
name: |
SERINE
|
roles: |
chemical component
|
formula: |
C5 H9 N O4
|
name: |
GLUTAMIC ACID
|
roles: |
chemical component
|
formula: |
C4 H8 N2 O3
|
name: |
ASPARAGINE
|
roles: |
chemical component
|
formula: |
C2 H5 N O2
|
name: |
GLYCINE
|
roles: |
chemical component
|
formula: |
C6 H10 N3 O2 1
|
name: |
HISTIDINE
|
roles: |
chemical component
|
formula: |
C6 H15 N4 O2 1
|
name: |
ARGININE
|
roles: |
chemical component
|
formula: |
C6 H13 N O2
|
name: |
ISOLEUCINE
|
roles: |
chemical component
|
formula: |
C9 H11 N O2
|
name: |
PHENYLALANINE
|
roles: |
chemical component
|
formula: |
C5 H11 N O2
|
name: |
VALINE
|
roles: |
chemical component
|
formula: |
C6 H15 N2 O2 1
|
name: |
LYSINE
|
roles: |
chemical component
|
formula: |
C4 H9 N O3
|
name: |
THREONINE
|
roles: |
chemical component
|
formula: |
C9 H11 N O3
|
name: |
TYROSINE
|
roles: |
chemical component
|
formula: |
C6 H13 N O2
|
name: |
LEUCINE
|
roles: |
chemical component
|
formula: |
C11 H12 N2 O2
|
name: |
TRYPTOPHAN
|
roles: |
chemical component
|
formula: |
C5 H11 N O2 S
|
name: |
METHIONINE
|
roles: |
chemical component
|
formula: |
C8 H15 N O6
|
name: |
N-ACETYL-D-GLUCOSAMINE
|
roles: |
chemical component
|
formula: |
C6 H12 O6
|
name: |
BETA-D-MANNOSE
|
roles: |
chemical component
|
formula: |
C6 H12 O6
|
name: |
ALPHA-D-MANNOSE
|
roles: |
chemical component
|
formula: |
CA 2
|
name: |
CALCIUM ION
|
roles: |
chemical component
|
formula: |
CL -1
|
name: |
CHLORIDE ION
|
roles: |
chemical component
|
formula: |
H2 O
|
name: |
WATER
|
roles: |
chemical component
|
name: |
Ntn1
|
name: |
X-RAY DIFFRACTION
|
ID: |
pdb:4OVE
|
ID: |
rcsb:RCSB084996
|
accessURL: | https://files.rcsb.org/download/4OVE.xml.gz |
storedIn: |
Protein Data Bank
|
qualifier: |
gzip compressed
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
PDBML/XML
|
accessType: |
download
|
authentication: |
none
|
authorization: |
none
|
accessURL: | https://files.rcsb.org/download/4OVE.pdb.gz |
storedIn: |
Protein Data Bank
|
qualifier: |
gzip compressed
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
PDB Format
|
accessType: |
download
|
authentication: |
none
|
authorization: |
none
|
accessURL: | https://files.rcsb.org/download/4OVE.cif.gz |
storedIn: |
Protein Data Bank
|
qualifier: |
gzip compressed
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
PDBx/mmCIF
|
accessType: |
download
|
authentication: |
none
|
authorization: |
none
|
accessURL: | http://www.rcsb.org/pdb/download/downloadFile.do?fileFormat=FASTA&compression=NO&structureId=4OVE |
storedIn: |
Protein Data Bank
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
FASTA
|
accessType: |
download
|
authentication: |
none
|
authorization: |
none
|
accessURL: | https://files.rcsb.org/download/4OVE-sf.cif.gz |
storedIn: |
Protein Data Bank
|
qualifier: |
gzip compressed
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
CIF
|
accessType: |
download
|
authentication: |
none
|
authorization: |
none
|
accessURL: | https://files.rcsb.org/download/4OVE.pdb1.gz |
storedIn: |
Protein Data Bank
|
qualifier: |
gzip compressed
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
PDB Format (A)
|
accessType: |
download
|
authentication: |
none
|
authorization: |
none
|
accessURL: | http://www.rcsb.org/pdb/explore/jmol.do?structureId=4OVE&bionumber=1 |
storedIn: |
Protein Data Bank
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
JSmol
|
accessType: |
view
|
authentication: |
none
|
authorization: |
none
|
abbreviation: |
wwPDB
|
homePage: | http://www.wwpdb.org |
ID: |
SCR:006555
|
name: |
Worldwide Protein Data Bank
|
abbreviation: |
PDB
|
homePage: | http://www.rcsb.org/pdb/![]() |
ID: |
SCR:012820
|
name: |
Protein Data Bank
|
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