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Title: Somatic Mutations in Variant and IGHV4-34 Expressing Hairy Cell Leukemia      
Identifier:
phs000671.v1.p1
description:
To understand the genetic mechanisms driving variant and IGHV4-34 expressing hairy-cell leukemia, we performed whole exome sequencing of tumor/normal pairs from ten patients.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000671.v1.p1
authentication: simpleLogin
none
authorization:
none
duaIndividual
name:
Leukemia, Hairy Cell
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
Paul S. Meltzer, PhD, MD
roles:
Principal Investigator
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
Robert J. Kreitman, MD
roles:
Principal Investigator
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
Joshua J. Waterfall, PhD
roles:
Investigator
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
Evgeny Arons, PhD
roles:
Investigator
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
Robert L. Walker
roles:
Investigator
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
Marbin Pineda
roles:
Investigator
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
Laura Roth
roles:
Investigator
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
J. Keith Killian, MD, PhD
roles:
Investigator
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
Ogan D. Abaan, PhD
roles:
Investigator
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
Sean R. Davis, MD, PhD
roles:
Investigator
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
Intramural Research Program
roles:
Funding Source
affiliations:
Hairy Cell Leukemia Research Foundation, Inc. Deerfield, IL, USA
name:
Hairy Cell Leukemia Research Foundation
roles:
Funding Source
affiliations:
Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
name:
Center for Cancer Research, National Cancer Institute, National Institutes of Health
roles:
Institution
performedBy:
TitleNameInstitute Principal InvestigatorPaul S. Meltzer, PhD, MDCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA Principal InvestigatorRobert J. Kreitman, MDCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA InvestigatorJoshua J. Waterfall, PhDCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA InvestigatorEvgeny Arons, PhDCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA InvestigatorRobert L. WalkerCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
downloadURL: https://dbgap.ncbi.nlm.nih.gov/aa/wga.cgi?page=DUC&view_pdf&stacc=phs000671.v1.p1
Identifier:
phs000671.v1.p1_policy
name:
Data Use Certificate
Identifier:
1
name:
Health/Medical/Biomedical (MDS)
alternateIdentifiers:
yes
selectionCriteria:

All patients have either IGHV4-34 expressing classic hairy cell leukemia, IGHV4-34 expressing variant hairy-cell leukemia, or IGHV4-34 non-expressing variant hairy-cell leukemia.

dateReleased:
10-18-2013
version:
phs000671.v1.p1
dateModified:
10-18-2013
abbreviation:
NCI
name:
NCI
ID:
0
name:
dbGaP

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