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Metadata

Name
Acceleration of Recovery From General Anesthesia - Efficacy of Isocapnic Hyperpnoea in Obese Patients Undergoing Isoflurane Anesthesia
Repository
ClinicalTrials.gov
Identifier
clinicaltrials:NCT00752492
Description
Faster recovery from anesthesia is important for obese patients because they are at high risk
of respiratory complications following tracheal extubation. Isoflurane has several properties
that make it a preferable agent for anesthesia in obese patients. Its main limitation is a
longer recovery time due to slower elimination in comparison to other agents. Elimination of
isoflurane from the lungs can be accelerated by increasing in patient's minute ventilation,
which decreases the level of CO2 in blood (hypocapnia).Isocapnic Hyperpnoea (IH) is a method
allowing increased ventilation and therefore enhancement of the elimination of inhalation
agents while maintaining a normal blood CO2 level. The investigators will compare recovery
time from isoflurane anesthesia in obese patients during standard anesthesia management
protocol (control) to a group treated with IH.
Data or Study Types
clinical trial
Keywords
Recovery of obese patient from isoflurane anesthesia, obesity, Isocapnic hyperpnoea, isoflurane
Source Organization
Unknown
Access Conditions
available
Year
2008
Access Hyperlink
https://clinicaltrials.gov/ct2/show/NCT00752492

Distributions

  • Encoding Format: HTML ; URL: https://clinicaltrials.gov/ct2/show/results/NCT00752492
This project was funded in part by grant U24AI117966 from the NIH National Institute of Allergy and Infectious Diseases as part of the Big Data to Knowledge program. We thank all members of the bioCADDIE community for their valuable input on the overall project.