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Metadata

Name
Efficacy of Epidiolex in Patients With Electrical Status Epilepticus of Sleep (ESES).
Repository
ClinicalTrials.gov
Identifier
clinicaltrials:NCT04721691
Description
This study aims to assess the efficacy of Epidiolex in patients with ESES. ESES is
characterized by sleep potentiated spikes with a spike index greater than 85% (conventional
definition) and 50% (new definition)1. Several drugs including: steroids, intravenous Gama
globulin, Clobazam, other benzodiazepines, Valproic acid, and other anti-epileptic drugs have
been tried with mixed benefits2,3. Cannabidiol (CBD) would provide a novel mechanism of
action to assess for its efficacy in this population. This will be a double-blind
placebo-controlled crossover clinical trial.
Data or Study Types
clinical trial
Keywords
ESES, Pediatric, Neurology
Source Organization
Unknown
Access Conditions
available
Year
2020
Access Hyperlink
https://clinicaltrials.gov/ct2/show/NCT04721691

Distributions

  • Encoding Format: HTML ; URL: https://clinicaltrials.gov/ct2/show/results/NCT04721691
This project was funded in part by grant U24AI117966 from the NIH National Institute of Allergy and Infectious Diseases as part of the Big Data to Knowledge program. We thank all members of the bioCADDIE community for their valuable input on the overall project.