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Metadata

Name
A Study to Evaluate the Safety and Immunogenicity of a Candidate Ebola Vaccine in Children
Repository
ClinicalTrials.gov
Identifier
clinicaltrials:NCT02548078
Description
The purpose of this study is to assess the safety and reactogenicity of a single IM dose of
the GSK3390107A (ChAd3 EBO-Z) vaccine, overall and in children aged 1 to 5, 6 to 12, and 13
to 17 years, separately.

Considering the risk of exposure to Ebola and the potential (based on animal data) for the
investigational GSK3390107A (ChAd3-EBO-Z) vaccine to afford at least partial protection, all
children in the study will receive the investigational GSK3390107A (ChAd3 EBO-Z) vaccine. The
children in the Group GSK3390107A+Nimenrix will receive the investigational GSK3390107A
(ChAd3-EBO-Z) vaccine at Day 0 of the study, whereas the children in the Group
Nimenrix+GSK3390107A will receive Nimenrix at Day 0 (as a control). At Month 6, the children
in the Group Nimenrix+GSK3390107A will receive the investigational GSK3390107A (ChAd3-EBO-Z)
vaccine (provided that no safety concerns are raised), whereas the children in the Group
GSK3390107A+Nimenrix will receive Nimenrix.
Data or Study Types
clinical trial
Source Organization
Unknown
Access Conditions
available
Year
2015
Access Hyperlink
https://clinicaltrials.gov/ct2/show/NCT02548078

Distributions

  • Encoding Format: HTML ; URL: https://clinicaltrials.gov/ct2/show/results/NCT02548078
This project was funded in part by grant U24AI117966 from the NIH National Institute of Allergy and Infectious Diseases as part of the Big Data to Knowledge program. We thank all members of the bioCADDIE community for their valuable input on the overall project.