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Metadata

Name
Erlotinib Pharmacokinetics During Doxycycline Treatment for Erlotinib-induced Rash
Repository
ClinicalTrials.gov
Identifier
clinicaltrials:NCT00803842
Description
A side effect occurring in a majority of patients taking erlotinib (Tarceva®) consists of a
skin rash. Sometimes, symptoms associated with the rash necessitate erlotinib dose reduction
or discontinuation. Some physicians have successfully treated the erlotinib-induced rash with
doxycycline. At the same time, it has been observed that in patients who develop the
erlotinib rash, the cancers respond better to erlotinib treatment. This research study is
designed to determine how well doxycycline treats the erlotinib rash and whether doxycycline
affects the blood levels of erlotinib.
Data or Study Types
clinical trial
Keywords
erlotinib, supportive care, rash
Source Organization
Unknown
Access Conditions
available
Year
2008
Access Hyperlink
https://clinicaltrials.gov/ct2/show/NCT00803842

Distributions

  • Encoding Format: HTML ; URL: https://clinicaltrials.gov/ct2/show/results/NCT00803842
This project was funded in part by grant U24AI117966 from the NIH National Institute of Allergy and Infectious Diseases as part of the Big Data to Knowledge program. We thank all members of the bioCADDIE community for their valuable input on the overall project.