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Metadata

Name
Phase II Trial of Talazoparib in BRCA1/2 Wild-type HER2-negative Breast Cancer and Other Solid Tumors
Repository
ClinicalTrials.gov
Identifier
clinicaltrials:NCT02401347
Description
The aim of this single-arm phase 2 clinical trial is to evaluate the anti-cancer activity of
Talazoparib (also known as BMN 673) in patients with advanced breast cancer with specific
genetic or tumor genomic alterations. Patients with either triple-negative or HER2-negative
breast cancer are eligible.
Data or Study Types
clinical trial
Keywords
HRD assay score, PALB2 mutation, MRE11 mutation, BRIP1 mutation, Rad51d mutation, CHEK2 mutation, NBN mutation, BARD1 mutation, PTEN mutation, Rad50 mutation, ATR mutation, ATM mutation, Rad51c mutation, FANC mutation
Source Organization
Unknown
Access Conditions
available
Year
2015
Access Hyperlink
https://clinicaltrials.gov/ct2/show/NCT02401347

Distributions

  • Encoding Format: HTML ; URL: https://clinicaltrials.gov/ct2/show/results/NCT02401347
This project was funded in part by grant U24AI117966 from the NIH National Institute of Allergy and Infectious Diseases as part of the Big Data to Knowledge program. We thank all members of the bioCADDIE community for their valuable input on the overall project.