Metadata
- Name
- Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer
- Repository
- ClinicalTrials.gov
- Identifier
- clinicaltrials:NCT04146298
- Description
- This clinical trial will evaluate the safety and activity of mutant KRAS G12V-specific TCR
transduced T cell therapy for advanced pancreatic cancer patients who express the KRAS G12V
mutation and HLA-A*11:01 allele. The theoretical basis of this study is that mutant KRAS
antigen-specific TCR transduced autologous Tcells will target and kill HLA-matched mutant
KRAS cancer cells but not normal cells. - Data or Study Types
- clinical trial
- Keywords
- KRAS, adoptive cell therapy, pancreatic cancer, TCR transduced T cells
- Source Organization
- Unknown
- Access Conditions
- available
- Year
- 2019
- Access Hyperlink
- https://clinicaltrials.gov/ct2/show/NCT04146298
Distributions
- Encoding Format: HTML ; URL: https://clinicaltrials.gov/ct2/show/results/NCT04146298