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Metadata

Name
A Study to Evaluate Rucaparib in Patients With Solid Tumors and With Deleterious Mutations in HRR Genes
Repository
ClinicalTrials.gov
Identifier
clinicaltrials:NCT04171700
Description
A Phase 2, open-label, single-arm trial to evaluate the response of rucaparib in patients
with various solid tumors and with deleterious mutations in Homologous Recombination Repair
(HRR) genes.
Data or Study Types
clinical trial
Keywords
colorectal cancer, HRD, germline, fallopian tube cancer, prostate cancer, leiomyosarcoma, esophageal cancer, FANCA, primary peritoneal cancer, basket trial, platinum sensitive, gastric cancer, PARPi, locally advanced, endometrial cancer, bladder cancer, rucaparib, ovarian cancer, metastatic, RAD51C, platinum resistant, tumor agnostic, PALB2, BRCA1, sarcoma, somatic, lung cancer, CO-338, DNA repair, homologous recombination, pancreatic cancer, LODESTAR, HRR, RAD51D, cervical cancer, RAD51B, solid tumor, rare tumor, PARP inhibitor, BRIP1, colon cancer, ampullary carcinoma, BARD1, breast cancer, BRCA2, basket study, carcinosarcoma, RAD51
Source Organization
Unknown
Access Conditions
available
Year
2019
Access Hyperlink
https://clinicaltrials.gov/ct2/show/NCT04171700

Distributions

  • Encoding Format: HTML ; URL: https://clinicaltrials.gov/ct2/show/results/NCT04171700
This project was funded in part by grant U24AI117966 from the NIH National Institute of Allergy and Infectious Diseases as part of the Big Data to Knowledge program. We thank all members of the bioCADDIE community for their valuable input on the overall project.