Metadata
- Name
- Expression data from mouse liver after Acetaminophen intoxication
- Repository
- Gemma
- Identifier
- gemma.experiment:1377
- Description
- Acetaminophen (APAP) is the most widely used analgesic in the United States. Its acute overdose causes liver damage by inducing localized centrilobular cell death. Because of widespread use, APAP toxicity has become the most frequent cause of acute liver failure. Many factors have been associated with the susceptibility of APAP-induced liver injuries, however, few of them have been confirmed and used in the clinical setting. We tried to identify the subset of factors that could affect susceptibility to APAP-induced liver injury by an integrative genetic, transcriptional and 2-D-NMR-based metabolomic analysis across a panel of inbred mouse strains.
Last Updated (by provider): Aug 14 2009
Contributors: Kimberly Dolim Zhaomei Zhang Jimmy Jung Erin Farrell Peng Lu - Data or Study Types
- gene expression
- Keywords
- functional genomics
- Source Organization
- University of British Columbia
- Access Conditions
- available
- Access Hyperlink
- www.chibi.ubc.ca/Gemma/expressionExperiment/showExpressionExperiment.html?id=1377
Distributions
- Encoding Format: HTML ; URL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE17649
- Encoding Format: TSV ; URL: http://www.chibi.ubc.ca/Gemma/expressionExperiment/showExpressionExperiment.html?id=1377
- Encoding Format: TSV ; URL: http://www.chibi.ubc.ca/Gemma/expressionExperiment/showExpressionExperiment.html?id=1377