Metadata
- Name
- Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers
- Repository
- ClinicalTrials.gov
- Identifier
- clinicaltrials:NCT04710407
- Description
- To evaluate the intrapulmonary pharmacokinetics (PK), including ELF and AM concentrations, of
SPR859 (tebipenem) compared to plasma concentrations of SPR859 (tebipenem) (the active moiety
in plasma of the prodrug SPR994) in nonsmoking healthy adult volunteers. - Data or Study Types
- clinical trial
- Keywords
- pharmacokinetics, tebipenem, epithelial lining fluid (ELF), TBPM-PI-HBr, alveolar macrophages (AM), intrapulmonary
- Source Organization
- Unknown
- Access Conditions
- available
- Year
- 2021
- Access Hyperlink
- https://clinicaltrials.gov/ct2/show/NCT04710407
Distributions
- Encoding Format: HTML ; URL: https://clinicaltrials.gov/ct2/show/results/NCT04710407