Metadata

Name

SGCZ sarcoglycan, zeta

Repository

HGVS Locus Specific Mutation Databases

Identifier

doi:608113

Description

The dystrophin glycoprotein complex (DGC) is found at the plasma membrane of muscle cells, where it provides a link between the cytoskeleton and the extracellular matrix. A subcomplex within the DGC, the sarcoglycan complex, associates with dystrophin and mediates muscle membrane stability. Sarcoglycans are asparagine-linked glycosylated proteins with single transmembrane domains. The sarcoglycan complex requires coordinated translation and assembly of its subunits for maintenance in the muscle membrane (summary by {1:Wheeler et al., 2002}).

Data or Study Types

gene expression

Source Organization

Human Genome Variation Society

Access Conditions

available

Year

2016