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Metadata

Name
EXPert System, ALImentary
Repository
ClinicalTrials.gov
Identifier
clinicaltrials:NCT03208699
Description
Eating disorders (ED) are often undetected in the general population resulting in delayed
treatment. The SCOFF questionnaire has been validated for eating disorders screening in
primary care, but does not identify the type of eating disorder.

Objective: Investigators evaluated the performance of a clinical algorithm (ExpaliTM)
combining answers to SCOFF questionnaire with Body Mass Index (BMI) to identify four Broad
Categories of ED derived from DSM-5.

Design: Clinical algorithm (ExpaliTM) was developped from 104 combinations of BMI levels and
answers to five SCOFF questions. Two senior ED specialists allocated each combination to one
of the four Broad Categories of ED (DSM-5 diagnostics): restrictive disorder (anorexia
nervosa typical, atypical and restrictive food intake disorders), bulimic disorder (typical
and with low frequency or duration), hyperphagic disorder (binge eating disorders typical and
with low frequency or duration) and other specified ED. The performance of ExpaliTM was
evaluated on data from patients referred to the Nutrition Department including a precise
DSM-5 diagnosis of ED, a positive SCOFF test (at least 2 "yes" answers) and BMI. Sensitivity,
specificity values with a 95% confidence interval (95% CI) and Youden index were calculated
for each category.
Data or Study Types
clinical trial
Keywords
bulimia, anorexia
Source Organization
Unknown
Access Conditions
available
Year
2017
Access Hyperlink
https://clinicaltrials.gov/ct2/show/NCT03208699

Distributions

  • Encoding Format: HTML ; URL: https://clinicaltrials.gov/ct2/show/results/NCT03208699
This project was funded in part by grant U24AI117966 from the NIH National Institute of Allergy and Infectious Diseases as part of the Big Data to Knowledge program. We thank all members of the bioCADDIE community for their valuable input on the overall project.