<< Go Back

Metadata

Name
Patient Preference for Mouthpiece Ventilation
Repository
ClinicalTrials.gov
Identifier
clinicaltrials:NCT03867721
Description
BACKGROUND:

Patients with severe neuromuscular disorders (NMDs) are likely to develop progressive
respiratory insufficiency, leading to noninvasive ventilation during the night and, later,
during night and day. Ventilation via a mouthpiece (MPV) is an elegant option to offer
daytime ventilation. The patient preference regarding the ideal material for daytime MPV is
unclear.

OBJECTIVES:

The purpose of this study was to determine which ventilator, tubing support and mouthpiece
was most effective and preferred by patients with NMDs.

METHODS:

Two separate MPV equipment sets were compared in 20 patients with NMDs in a randomized
cross-over study. The first set consisted in a non-dedicated ventilator for MPV (PB560,
Covidien) combined with a customized tubing support on the shoulders and a plastic angled
mouthpiece. The second set included an MPV-dedicated ventilator (Trilogy 100, Philips
Respironics) without back-up rate and kiss trigger combined with a commercially available
tubing support and a silicone straw mouthpiece. The Borg dyspnea score, the free time without
noninvasive ventilation, the transcutaneous oxygen saturation (SpO2) and carbon dioxide
tension (TcCO2) were recorded without and with MPV. A 17-items list assessing the patient
perception about MPV sets was completed.
Data or Study Types
clinical trial
Source Organization
Unknown
Access Conditions
available
Year
2019
Access Hyperlink
https://clinicaltrials.gov/ct2/show/NCT03867721

Distributions