Metadata
- Name
- Transcriptome analysis ofLu134A cells following ASCL1 knockdown and SBC5 cells transfected by miR455-3p mimic
- Repository
- Gemma
- Identifier
- gemma.experiment:20626
- Description
- Molecular subtypes of SCLC have been defined by the expression status of ASCL1, NEUROD1, YAP1, and POU2F3 transcription regulators. ASCL1 knockdown resulted in decreased and increased expression of miR-375 and miR-455-3p, respectively. Analyses of publicly available transcriptome datasets suggested that miR-375 induced by ASCL1 is involved in YAP1 suppression whereas miR-455-3p is higher in non-neuroendocrine SCLC cells lacking ASCL1 expression.
At time of import, last updated (by provider) on: Jul 25 2021
Contributors: ; [Takahide Nagase, Akira Saito, Masafumi Horie, Kazuko Miyakawa, Naoya Miyashita] - Data or Study Types
- gene expression
- Keywords
- functional genomics
- Source Organization
- University of British Columbia
- Access Conditions
- available
- Access Hyperlink
- www.chibi.ubc.ca/Gemma/expressionExperiment/showExpressionExperiment.html?id=20626
Distributions
- Encoding Format: HTML ; URL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE180314
- Encoding Format: TSV ; URL: http://www.chibi.ubc.ca/Gemma/expressionExperiment/showExpressionExperiment.html?id=20626
- Encoding Format: TSV ; URL: http://www.chibi.ubc.ca/Gemma/expressionExperiment/showExpressionExperiment.html?id=20626