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Metadata

Name
Efficacy of Irbesartan/Hydrochlorothiazide Versus Valsartan/Hydrochlorothiazide in Mild to Moderate Hypertension
Repository
ClinicalTrials.gov
Identifier
clinicaltrials:NCT00500604
Description
The primary objective is to compare the efficacy of irbesartan/hydrochlorothiazide 300/25mg
against valsartan/hydrochlorothiazide 160/25mg in reducing mean systolic blood pressure (SBP)
as measured by home blood pressure monitoring (HBPM) after 24 weeks compared with baseline.

The secondary objectives are:

- To compare the percentage of patients with normal blood pressure as measured by HBPM and
at the doctor's office at weeks 16 and 24

- To compare the differences in mean Diastolic Blood Pressure (DBP), mean morning and
evening SBP and DBP evaluated by HBPM at weeks 16 and 24

- To compare the difference in mean SBP evaluated by HBPM at week 16

- To compare the differences in mean SBP and DBP evaluated at the doctor's office at weeks
16 and 24

- To determine the incidence and severity of adverse events
Data or Study Types
clinical trial
Source Organization
Unknown
Access Conditions
available
Year
2007
Access Hyperlink
https://clinicaltrials.gov/ct2/show/NCT00500604

Distributions

  • Encoding Format: HTML ; URL: https://clinicaltrials.gov/ct2/show/results/NCT00500604
This project was funded in part by grant U24AI117966 from the NIH National Institute of Allergy and Infectious Diseases as part of the Big Data to Knowledge program. We thank all members of the bioCADDIE community for their valuable input on the overall project.