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Metadata

Name
Closed Loop Ventilation With High Tidal Volumes and Safe Transpulmonary Pressure in COPD (COPD-SAFE)
Repository
ClinicalTrials.gov
Identifier
clinicaltrials:NCT04089111
Description
This study evaluates the safety and efficacy of high tidal volumes generated by "Adapted
Support Ventilation (ASV) mode' in mechanically ventilated severe COPD patients. Every
patient will be ventilated consecutively with ASV and Volume Control (VC) modes at 2
different levels of minute volume in 2 sets. ASV mode is expected to be safe measured by
adequate inspiratory transpulmonary pressures and expected to be as effective as VC mode with
lower intrinsic positive end expiratory pressure (iPEEP) levels.
Data or Study Types
clinical trial
Keywords
Safety, Adaptive Support Ventilation, Intrinsic PEEP, Mechanical ventilation, Transpulmonary pressure
Source Organization
Unknown
Access Conditions
available
Year
2019
Access Hyperlink
https://clinicaltrials.gov/ct2/show/NCT04089111

Distributions

  • Encoding Format: HTML ; URL: https://clinicaltrials.gov/ct2/show/results/NCT04089111
This project was funded in part by grant U24AI117966 from the NIH National Institute of Allergy and Infectious Diseases as part of the Big Data to Knowledge program. We thank all members of the bioCADDIE community for their valuable input on the overall project.