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Title: Transcription profiling by array of Arabidopsis polyploidy-associated transcriptional gene silencing (paTGS) mutants ddm1-12 and hog1-7 against wild type controls      
availability:
available
aggregation:
instance of dataset
privacy:
not applicable
refinement:
curated
dateReleased:
04-29-2015
ID:
E-GEOD-17496
description:
A case of transcriptional gene silencing, originally observed in tetraploid Arabidopsis plants, created an epiallele resistant to many mutations or inhibitor treatments that activate other suppressed genes. This raised the question about the molecular basis of this extreme stability. A combination of forward and reverse genetics, transcriptome profiling and drug application provides evidence for a double safeguard system that is only alleviated upon the simultaneous removal of both DNA methylation and histone methylation by loss of DDM1 or HOG1 acitivity. Three biological replicates per line are provided. C2S1 = Wt line; hog1-7=774; ddm1-12=1135
keywords:
transcription profiling by array
format:
HTML
storedIn:
Array Express
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not compressed
accessType:
landing page
authorization:
none
authentication:
none
primary:
true
accessURL: https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-17496
format:
JSON
storedIn:
OmicsDI
qualifier:
not compressed
accessType:
download
authorization:
none
authentication:
none
primary:
false
accessURL: www.omicsdi.org/ws/dataset/arrayexpress-repository/E-GEOD-17496.json
format:
XML
storedIn:
OmicsDI
qualifier:
not compressed
accessType:
download
authorization:
none
authentication:
none
primary:
false
accessURL: http://www.omicsdi.org/ws/dataset/arrayexpress-repository/E-GEOD-17496.xml
ID:
SCR:014747
name:
Omics Discovery Index
abbreviation:
OmicsDI
homePage: http://www.omicsdi.org/