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Title: CKR_CONRA      
description:
Conantokin-R Divalent metal cation; via 4-carboxyglutamate Divalent metal cation; via 4-carboxyglutamate Significant for the subtype selectivity between NR2B/GRIN2B and NR2D/GRIN2D (potent for NR2B/GRIN2B but not for NR2D/GRIN2D) 4-carboxyglutamate 4-carboxyglutamate 4-carboxyglutamate 4-carboxyglutamate No change in potency for NR2B/GRIN2B; 3-fold increase in potency for NR2D/GRIN2D Little decrease in potency for NR2B; little decrease in potency for NR2A No change in potency for NR2B; No change in potency for NR2A Little increase in potency for NR2B; little increase in potency for NR2A No change in potency for NR2B/GRIN2B; 3-fold increase in potency for NR2D/GRIN2D Important decrease in potency for NR2B/GRIN2B; complete loss in potency for NR2D/GRIN2D
types:
sequence
dateReleased:
04-26-2005
ID:
P58806
privacy:
not applicable
keywords:
Direct protein sequencing
Disulfide bond
Gamma-carboxyglutamic acid
Ion channel impairing toxin
Ionotropic glutamate receptor inhibitor
Metal-binding
Neurotoxin
Postsynaptic neurotoxin
Secreted
Signal
Toxin
availability:
available
refinement:
curated
version:
2
aggregation:
instance of dataset
name:
Conus radiatus
strain:
Rayed cone
ID:
ncbitax:61198
name:
Conantokin-R
authorization:
none
authentication:
none
format:
HTML
storedIn:
UniProt
accessType:
landing page
qualifier:
not compressed
accessURL: http://www.uniprot.org/uniprot/P58806
license:
Creative Commons Attribution-NoDerivs License
authorization:
none
authentication:
none
format:
FASTA
storedIn:
UniProt
accessType:
download
qualifier:
not compressed
accessURL: http://www.uniprot.org/uniprot/P58806.fasta
license:
Creative Commons Attribution-NoDerivs License
name:
European Bioinformatics Institute
abbreviation:
EMBL-EBI
ID:
SCR:004727
homePage: http://www.ebi.ac.uk/
name:
UniProt
abbreviation:
UniProt
ID:
SCR:002380
homePage: http://www.uniprot.org/

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