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Title: ESPL1_HUMAN      
description:
Separin Peptidase C50 Cleavage; by autolysis Cleavage; by autolysis Phosphoserine Phosphoserine Phosphoserine Phosphoserine In isoform 2. In dbSNP:rs1318648. In dbSNP:rs34424268. In dbSNP:rs34130634. In dbSNP:rs35428211. In dbSNP:rs34396464. In dbSNP:rs1110719. Abolishes phosphorylation at this site, as well as the negative regulation due to phosphorylation Abolishes autocleavage; when associated with R-1178; E-1181; R-1207 and E-1210. Does not affect the protease function Abolishes autocleavage; when associated with A-1181 and A-1210 Does not affect autocleavage. Does not affect the protease function Abolishes autocleavage; when associated with A-1161 and A-1210 Strongly reduces autocleavage at this site, but enhances autocleavage at site 1. Does not affect the protease function Abolishes autocleavage; when associated with A-1161 and A-1281 Abolishes protease activity (in Ref. 1; AAR18247) (in Ref. 1; AAR18247) (in Ref. 1; AAR18247 and 2; BAA11482) (in Ref. 1; AAR18247 and 2; BAA11482) (in Ref. 1; AAR18247 and 2; BAA11482) (in Ref. 1; AAR18247 and 2; BAA11482)
types:
sequence
dateReleased:
10-05-2010
ID:
Q14674
privacy:
not applicable
keywords:
Alternative splicing
Autocatalytic cleavage
Chromosome partition
Complete proteome
Cytoplasm
Direct protein sequencing
Hydrolase
Nucleus
Phosphoprotein
Polymorphism
Protease
Reference proteome
Thiol protease
availability:
available
refinement:
curated
version:
3
aggregation:
instance of dataset
name:
Homo sapiens
strain:
Human
ID:
ncbitax:9606
name:
Separin
authorization:
none
authentication:
none
format:
HTML
storedIn:
UniProt
accessType:
landing page
qualifier:
not compressed
accessURL: http://www.uniprot.org/uniprot/Q14674
license:
Creative Commons Attribution-NoDerivs License
authorization:
none
authentication:
none
format:
FASTA
storedIn:
UniProt
accessType:
download
qualifier:
not compressed
accessURL: http://www.uniprot.org/uniprot/Q14674.fasta
license:
Creative Commons Attribution-NoDerivs License
name:
European Bioinformatics Institute
abbreviation:
EMBL-EBI
ID:
SCR:004727
homePage: http://www.ebi.ac.uk/
name:
UniProt
abbreviation:
UniProt
ID:
SCR:002380
homePage: http://www.uniprot.org/

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