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Title: Cocaine Use Reduction with Buprenorphine (CURB)      
ID:
NIDA-CTN-0048
creators:
Walter Ling, M.D.
privacy:
information not available
keywords:
naltrexone; cocaine; buprenorphine
refinement:
curated
types:
clinical trial
dateReleased:
04-24-2015
aggregation:
instance of dataset
availability:
available
description:
This was a randomized, controlled trial that enrolled 302 cocaine-dependent participants who had either past-year opioid dependence or past-year opioid abuse or past-year opioid use with a history of opioid dependence during the lifetime. Participants were randomized to one of three treatment arms: 1) placebo plus naltrexone, 2) 4mg buprenorphine plus naltrexone, and 3) 16mg buprenorphine plus naltrexone. Participants received 8 weeks of pharmacotherapy, with thrice weekly clinic visits. The primary aim of the study was to compare the number of cocaine use days during the 30-day evaluation period (the final 30 days of active medication administration prior to taper; days 25-54) amongst the treatment groups. The study also evaluated a number of secondary outcome measures.
name:
Homo sapiens
ID:
SCR:011440
homePage: http://www.nida.nih.gov/
abbreviation:
NIDA
name:
National Institute on Drug Abuse
ID:
SCR:002002
homePage: http://datashare.nida.nih.gov/
abbreviation:
CTN
name:
Clinical Trials Network Data Share