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Title: Telemetric and Holter ECG Warehouse (THEW): Occluded Artery Trial (Stony Brooke Univ.)      
dateReleased:
02-02-2009
description:
OAT:Defibrillator in Non-Ischemic Cardiomyopathy Treatment Evaluation Trial IDENTIFICATION : E-OTH-03-0802-018 The database (E-OTH-03-0802-018) hosts the Holter ECGs recorded during the OAT that was designed to determine whether opening an occluded infarcted artery (PCI) 3-28 days after an acute myocardial infarction in high-risk asymptomatic patients reduces the composite endpoint of mortality, recurrent myocardial infarction, and hospitalization for class IV congestive heart failure over a three year follow- up. The trial was conducted as a randomized study involving 2166 stable patients who had total occlusion of the infarct-related artery 3 to 28 days after myocardial infarction and who met a high-risk criterion (an ejection fraction of <50% or proximal occlusion). Of these patients, 1082 were assigned to routine PCI and stenting with optimal medical therapy, and 1084 were assigned to optimal medical therapy alone. The trial demonstrated that PCI did not reduce the occurrence of death, reinfarction, or heart failure. Furthermore, there was a trend toward excess reinfarction during 4 years of follow-up in stable patients with occlusion of the infarct-related artery 3 to 28 days after myocardial infarction. Shared by New-York School of Medicine and SUNY, this new database includes 802 10-min ECG recordings from a subset of 223 patients enrolled in the OAT trial (3.6 Holter recordings per patient in average). The access to this database requires the user(s) to submit a short research proposal that will be reviewed by an ad-hoc committee consisting of the principal investigators of the OAT trial and its Holter-related substudy (i.e. Prof. Judith Hochman, MD from the NYU Langone Medical Center and Prof. Eric Rashba from Stony Brooke University of Medicine).
privacy:
information not available
aggregation:
instance of dataset
availability:
THEW Data Use Agreements (see Thew website for details)
refinement:
raw
ID:
handle:11614/1643
types:
image
ID:
doi:10.1161/CIRCULATIONAHA.108.808626
accessURL: http://thew-project.org/register_main.htm
accesstypes:
Landing Page
storedIn:
CardioVascular Research Grid
authentication:
none
authorization:
none
abbreviation:
JHU
homePage: http://www.jhu.edu/
ID:
SCR:010247
name:
Johns Hopkins University
abbreviation:
CVRG
homePage: http://www.cvrgrid.org/
ID:
SCR:004472
name:
CardioVascular Research Grid

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