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Title: Cancer-cell intrinsic gene expression signatures minimise the confounding effects of intratumoural heterogeneity in colorectal cancer patient classification.      
keywords:
Transcriptome or Gene expression
ID:
PRJNA376109
description:
Stromal-derived intratumoural heterogeneity (ITH) has been shown to undermine molecular stratification of patients into appropriate prognostic/predictive subgroups. Using several clinically relevant colorectal cancer (CRC) gene expression signatures, we assessed the susceptibility of these signatures to the confounding effects of ITH using gene expression microarray data obtained from multiple tumour regions of a cohort of 24 patients, including central tumour, the tumour invasive front and lymph node metastasis. Overall design: Transcriptional profiles generated from matched central tumour, invasive front and lymph node regions from 24 colorectal cancer patients.
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA376109
authentication:
none
authorization:
none
name:
Homo sapiens
ncbiID:
ncbitax:9606
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject