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Title: Analyses of heterochromatin distributions in the mutatnts defective in an RNAi-heterochromatin positive feedback loop in Tetrahymena [ChIP]      
keywords:
Epigenomics
ID:
PRJNA343283
description:
In the ciliated protozoan Tetrahymena, an RNAi-mediated feedback loop is important for assembling heterochromatin on the sequences that are removed from the somatic genome by programmed DNA elimination. Because heterochromatin is formed exclusively on the eliminated sequences, some mechanism must inhibit this feedback loop at the boundaries of the eliminated sequences. In this study, we show that the HP1-like protein Coi6p, its interaction partners Coi7p and Lia5p, and the histone demethylase Jmj1p are crucial for confining the formation of heterochromatin to the eliminated sequences. Overall design: 26 to 32-nt small RNAs from verious mutants or from immuno precipitated with Argonaute proteins were analyzed by high-throughput sequencing
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA343283
authentication:
none
authorization:
none
name:
Tetrahymena thermophila
ncbiID:
ncbitax:5911
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject