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Title: Protein Kinase CK2 Controls the Fate Between Th17 Cell and Regulatory T Cell Differentiation      
keywords:
Transcriptome or Gene expression
ID:
PRJNA343123
description:
We report that CK2 inhibition with CX-4945 broadly suppresses Th17-associated effector and metabolic gene expression. CD4+ T cells were cultured in IL-6, IL-23 and TGFb1 for 72 h, in the absence of presence of 2 mM CX-4945, RNA-seq was performed and gene expression compared between the control and treatment groups. Overall design: RNA-seq was performed on 3 biological replicates in the control and treatment groups.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA343123
authentication:
none
authorization:
none
name:
Mus musculus
ncbiID:
ncbitax:10090
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject