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Title: complete sequence of plasmid harboring the 16S rRNA methyltransferase-encoding gene rmtH a : IncFIIK plasmid harbouring an amplification of 16S rRNA methyltransferase-encoding gene rmtH associated to mobile element ISCR2      
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ID:
PRJEB14121
description:
In this study, we report the complete sequence of a 114kb plasmid encoding the 16S rRNA methyltransferase-encoding gene rmtH. This plasmid was characterized in a carbapenemase-producing Klebsiella pneumoniae strain isolated in Lebanon. This is the first report of rmtH in a plasmid. The plasmid harbours an antibiotic resistance island associated to a novel composite transposon encoding the extended-spectrum β-lactamase SHV-12, RmtH and ISCR2 elements. ISCR2 elements and rmtH exhibit are unusual organization, suggesting a gene amplification due to the rolling-circle replication of ISCR2. We also identified a new hybrid toxin-antitoxin system in the backbone of the plasmid.
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJEB14121
authentication:
none
authorization:
none
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject