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Title: Characterization of an abiraterone ultra-responsive phenotype in castration-resistant prostate cancer patient-derived xenografts      
keywords:
Transcriptome or Gene expression
ID:
PRJNA339045
description:
To identify the molecular signature associated with abiraterone acetate (AA) response and mechanisms underlying AA resistance in castration-resistant prostate cancer patient-derived xenografts (PDXs). Overall design: SCID mice bearing LuCaP 136CR, 77CR, 96CR, and 35CR PDXs were treated with AA. Tumors response were followed, and tumors were harvested 7 days post-treatment (D7) and at end of study (EOS) for gene expression profiling using the Affymetrix Human Genome U219 Array Plate platform. Four replicates per PDX, treatment, and timepoint were profiled.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA339045
authentication:
none
authorization:
none
ID:
pmid:27993966
name:
Homo sapiens
ncbiID:
ncbitax:9606
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject