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Title: Molecular Changes in the Nasal Cavity after 5 days of N, N-dimethyl-p-toluidine Exposure      
keywords:
Transcriptome or Gene expression
ID:
PRJNA338495
description:
To identify nasal cavity transcripts differentially expressed due to treatment with N, N-dimethyl-p-toluidine (DMPT), we collected RNA during the from male F344/N rats exposed to 120 mg/kg DMPT, 5 days after DMPT exposure for animals 5-6 weeks of age. These samples were interrogated with the Affymetrix Rat Genome 230 2.0 GeneChip Array. A total of 2,561 gene transcripts were differentially expressed due to DMPT treatment (false discovery rate (FDR) < 0.05). Overall design: There were 2 groups and 5x replication for each group, for 10 total samples. The groups were (1) DMPT and (2) vehicle control. We compared vehicle control vs DMPT using ORIOGEN software. The permutation based p-values for each test were significant for FDR≤5%.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA338495
authentication:
none
authorization:
none
ID:
pmid:27099258
name:
Rattus norvegicus
ncbiID:
ncbitax:10116
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject
  • N01ES75561/ES/NIEHS NIH HHS/United States

  • Z99 ES999999/NULL/Intramural NIH HHS/United States

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