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Title: A novel target of CD274 involvement in AML development      
keywords:
Transcriptome or Gene expression
ID:
PRJNA336538
description:
We report abonormally expressed genes of MLL-AF9 induced CD274-/- AML mice by RNA-seq analysis. Cyclin D2 was found down-regulated in CD274 depleted AML LSCs, suggesting it might be a novel target gene of CD274 involvement in AML advancement. Overall design: Examination of differentially expressed genes in AML LSCs of wild type and CD274 knockout mice. Verification the function of selected gene in pathogenesis of AML involvement CD274 dysfunction.
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA336538
authentication:
none
authorization:
none
ID:
pmid:27855694
name:
Mus musculus
ncbiID:
ncbitax:10090
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject