Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Title: microRNA expression in postnatal mammary gland development -Pregnancy Day14 and Lactation day 2      
keywords:
Transcriptome or Gene expression
ID:
PRJNA317482
description:
Previoulsly miRNA expression profiling of the whole mammary gland across different stages of pregnancy and lactation has been performed in mice. Since mammary gland has both epithelial and stromal compartments, to specifically identify the miRNAs involved in the transition from pregnancy to lactation a process termed as secretory activation, expression profiling of isolated mammary epithelial cells (MECs) from four CD1 mice each at Pregnancy day 14 (P14) and Lactation day 2 (L2) was performed in the current study. Statistical analysis of the miRNA changes between P14 and L2 identified 32 miRNAs to be differentially expressed with a fold change greater than or equal to 2, of which, the majority of them declinied at the onset of lactation. Overall design: 4 replicates each from Pregnancy day 14 and Lactation day 2 were hybridized onto Affymetrix GeneChip® miRNA 1.0 ST Array (7,625 probesets)
accesstypes:
download
landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA317482
authentication:
none
authorization:
none
ID:
pmid:27729410
name:
Mus musculus
ncbiID:
ncbitax:10090
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject