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Title: miRNA expression profiling in human glioma stem cell upon TUG1 inhibition      
keywords:
Transcriptome or Gene expression
ID:
PRJNA317342
description:
Glioblastomas show heterogeneous histological features. These distinct phenotypic states are thought to be associated with the presence of glioma stem cells (GSCs), which are highly tumorigenic and self-renewing sub-population of tumor cells that have different functional characteristics. We found that TUG1, a long non-coding RNA (lncRNA), plays pivotal roles in maintaining the self-renewal properties of GSC. Some lncRNAs are known to act as a miRNA sponge in the cytoplasm, where lncRNAs bind to miRNAs and quench their activity. To investigate miRNA expression profiling in GSC upon TUG1 inhibition, we have performed microarray experiment using SurePrint G3 Human miRNA 8x60K Microarray (G4872A, Agilent Technologies). Overall design: Microarray experiment was performed as single-color hybridization on Agilent human miRNA catalog 8x60k array.
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA317342
authentication:
none
authorization:
none
ID:
pmid:27922002
name:
Homo sapiens
ncbiID:
ncbitax:9606
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject