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Title: BRD4 represses CBX5      
keywords:
Transcriptome or Gene expression
ID:
PRJNA313265
description:
BRD4 is amplified and/or up-regiulated in a subset of ovarian cancer which correlates with a poor survival siRNA sensitization screens in the presence of CHK1 inhibitor, LY2606368, identify BRD4 as a therapeutic target in ovarian cancer. BRD4 suppression by either siRNA or using JQ1 increases CBX5 expression Overall design: (i) BRD4 knockdown by siBRD4 in Ovcar8, performed in 3 replicates. (ii) BRD4 inhibition using JQ1 in Ovcar8, performed in 3 replicates.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA313265
authentication:
none
authorization:
none
name:
Homo sapiens
ncbiID:
ncbitax:9606
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject