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Title: Human Toxome Project, E2 and PPT induction of MCF-7 cells (NC series)      
keywords:
Transcriptome or Gene expression
ID:
PRJNA309846
description:
The central goal of the project is to define, experimentally verify, and systematically annotate pathways of endocrine disruption, as a proof of concept of mapping pathways of toxicity by systems toxicology. Microarray gene expression profiling is one of several -omics approaches used. Overall design: Gene expression was measured in MCF-7 cells after exposure to doses of 0.01 nM, 0.1 nM or 1nM estradiol (E2), 5 nM propyl pyrazole triol (PPT) or vehicle control for 4 or 8 hours. The experiment was repeated at two different institutions, Johns Hopkins University (JHU) and Brown University (BU), where three biological replicates were produced for each condition.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA309846
authentication:
none
authorization:
none
name:
Homo sapiens
ncbiID:
ncbitax:9606
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject