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Title: Homo sapiens strain:MCF7 : Genomic copy-number gain analysis of two MCF7 tamoxifen-resistant cell models      
keywords:
exome
ID:
PRJNA304008
description:
Endocrine resistance is a major obstacle in treating estrogen receptor α (ER)-positive (+) breast cancer. During the process of acquiring endocrine resistance, we hypothesize that genomic aberration may play an important role in contributing to the gene expression related to resistance phenotype. By using two independently developed MCF7 tamoxifen-resistant (TamR) cell models (L and RN), we applied next-generation exome-seq analysis focusing on the copy-number gain in these two TamR cell derivatives.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA304008
authentication:
none
authorization:
none
ID:
pmid:27791031
name:
Homo sapiens
ncbiID:
ncbitax:9606
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject
  • P01 CA080111/CA/NCI NIH HHS/United States

  • P30 CA125123/CA/NCI NIH HHS/United States

  • P30 AI036211/AI/NIAID NIH HHS/United States

  • P50 CA058183/CA/NCI NIH HHS/United States

  • S10 RR024574/RR/NCRR NIH HHS/United States

  • P50 CA186784/CA/NCI NIH HHS/United States

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