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Title: Noggin vs BMP4 overexpression Epidermis      
keywords:
Transcriptome or Gene expression
ID:
PRJNA134999
description:
The study was performed to determine if there were alterations in the total RNA pool among the epidermal keratinocytes of K14 promotor-driven noggin overexpression compared with K14 promotor-driven BMP4 overexpression transgenic animals, which will directly relate to cellular chemistry and immune and sensory function. The total study is also aimed at determining alterations of transcrption factors and/or regulation of gene function, including methylation states and micro RNA control in keratinocytes following sensory challenge, particularly neuropathic and chronic pain conditions. Keywords: Comparison of RNA expression between BMP4-oex and Nog-oex transgenic epidermal keratinocytes Overall design: Eight-ten epidermis strips were laser captured per animal, and six (6) animals were used per transgenic condition. Recovered RNA samples were pooled from 2 groups of 3 noggin transgenics and 2 groups of 3 BMP4 transgnics to create four pools for hybridization.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA134999
authentication:
none
authorization:
none
ID:
pmid:21641113
name:
Mus musculus
ncbiID:
ncbitax:10090
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject
  • P30 AR057216/AR/NIAMS NIH HHS/United States

  • 1P30AR057216-01/AR/NIAMS NIH HHS/United States

  • T32 DA007307/DA/NIDA NIH HHS/United States

  • R01 NS020778-26/NS/NINDS NIH HHS/United States

  • R01 NS020778/NS/NINDS NIH HHS/United States

  • T32 DA007307-03/DA/NIDA NIH HHS/United States

  • R01 NS020013/NS/NINDS NIH HHS/United States

  • R01 NS020013-26/NS/NINDS NIH HHS/United States

  • R01 NS020013-27/NS/NINDS NIH HHS/United States

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