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Title: miRNA expression of human samples of hepatoblastoma (HB) and normal and fetal liver      
dateReleased:
07-08-2011
description:
Forty-nine hepatoblastoma (HB) tumor specimens were profiled on a microarray containing 250human miRNA, in order to identify miR classifiers that could discriminate HBs with diverse prognosis, and to get insight on the functional mechanisms in which miRNAs are involved. Hierarchical unsupervised clustering of HB samples according to their miRNA expression profile identifies 2 tumor subgroups associated with different degree of differentiation, proliferation rate and invasive phenotype. As subset of these tumors is used as training set to build a mir classifier. When the signature is applied to an independent test set, an independent series of HB is classified patients into two groups associated with the clinical features identified in the first set of patients.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-20971
refinement:
raw
alternateIdentifiers:
20971
keywords:
functional genomics
dateModified:
07-19-2011
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-GEOD-10231
name:
OSU-CCC MicroRNA Microarray Version 2.0 [condensed version]
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-20971/E-GEOD-20971.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-20971/E-GEOD-20971.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE20971
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress
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