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Title: Quantitative analysis of thyroid response in zebrafish embryos      
dateReleased:
07-08-2011
description:
In the further study we have employed the Zebrafish gene expression microarray (v2) as a discovery platform to analysis the trancriptome of 5dpf (days post fertilization) embryos exposed from the 2dpf to 5dpf to nanomolar concrations of thyoid hormone. Only less than 5% genes were affected by the treatment. Gene ontology (GO) analyses show that these genes are involved in the haematopoietic system, visual function and skeletal system. Representatives of each GO functional groups were selected and quantified by real-time PCR to validate the microarray data and to use them as a quantitative biomarkers of thyroid receptor activator. The gene expression in Zebrafish was measured in 5 dpf's embryos under 72h Thyroid Hormone treatment at 50nM.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-23315
refinement:
raw
alternateIdentifiers:
23315
keywords:
functional genomics
dateModified:
07-19-2011
availability:
available
types:
gene expression
name:
Danio rerio
ID:
A-MEXP-1510
name:
Agilent D. rerio (Zebrafish) Oligo Microarray 4x44K 019161 G2519F 85 cols x 532 rows
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-23315/E-GEOD-23315.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-23315/E-GEOD-23315.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE23315
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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