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Title: Transcription profiling by array of H. sapiens liver cells to investigate global gene expression associated with the progression of NAFLD      
dateReleased:
07-12-2011
description:
Non-alcoholic fatty liver disease (NAFLD) is characterized by a series of pathological changes that can progress from simple fatty liver disease to non-alcoholic steatohepatitis (NASH). The objective of this study is to describe changes in global gene expression associated with the progression of NAFLD. This study is focused on the expression levels of genes responsible for the absorption, distribution, metabolism and excretion (ADME) of drugs. Differential gene expression between three clinically defined pathological groups; normal, steatosis and NASH was analyzed. The samples were diagnosed as normal, steatotic, NASH with fatty liver (NASH fatty) and NASH without fatty liver (NASH NF). Genome-wide mRNA levels in samples of human liver tissue were assayed with Affymetrix GeneChip® Human 1.0ST arrays
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MEXP-3291
refinement:
raw
keywords:
functional genomics
dateModified:
05-02-2014
creators:
Petr Novak
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-AFFY-183
name:
Affymetrix GeneChip Human Gene 1.0 ST Array [HuGene-1_0-st-v1](Release 29)
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MEXP-3291/E-MEXP-3291.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MEXP-3291/E-MEXP-3291.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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