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Title: ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila      
dateReleased:
12-10-2011
description:
Analysis of the effects of ATM loss on gene expression to identify causes of neurodegeneration. ATM levels were reduced ubiquitously via the temperature-sensitive ATM^8 allele, or via tissue-specific RNAi of ATM (ATMi) using the Gal4/UAS expression system in neurons (Elav-GAL4 and ElavC155-GAL4) or glial cells (Repo-GAL4). A 20-chip study using total RNA representing 2 replicates of 3 control genotypes (ATM^8/+, Repo-GAL4, and ElavC155-GAL4) and 3 experimental genotypes (ATM^8/ATM^8, Repo-ATMi, ElavC155-ATMi), and 4 replicates each of a control (Elav-GAL4) and experimental (Elav-ATMi) genotype
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-34315
refinement:
raw
alternateIdentifiers:
34315
keywords:
functional genomics
dateModified:
12-17-2011
availability:
available
types:
gene expression
name:
Drosophila melanogaster
ID:
A-GEOD-13782
name:
NimbleGen Drosophila melanogaster Gene expression array [DM4_3_60mer_expr]
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-34315/E-GEOD-34315.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-34315/E-GEOD-34315.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE34315
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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