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Title: Comparison of gene expression between wild type and AP2-L KO parasites      
dateReleased:
04-30-2012
description:
In the rodent malaria parasite Plasmodium berghei, we found that an AP2 family transcription factor designated AP2-L plays a critical role in the development of the liver stage. Using DNA microarray analysis we showed that the expression of several genes, including those of parasitophorous vacuole membrane proteins, was significantly decreased in the early liver stage of AP2-L-depleted parasites. Gene expression of P. berghei liver stages was compared between wild type and AP2-L KO parasites. Liver stage parasites were cultured for 24h using HepG2 cells. Ten and seven biologically independent experiments were performed for wild type and AP2-L KO parasites, respectively.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-34877
refinement:
raw
alternateIdentifiers:
34877
keywords:
functional genomics
dateModified:
05-11-2012
availability:
available
types:
gene expression
name:
Plasmodium berghei
ID:
A-GEOD-15092
name:
Agilent-031544 Custom Plasmodium berghei str. ANKA array [PBANKA1]
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-34877/E-GEOD-34877.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-34877/E-GEOD-34877.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE34877
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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