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Title: Escape from Immunosurveillance in Pancreatic Cancer is Mediated by the Stromal Cell Expressing Fibroblast Activation Protein-Alpha      
dateReleased:
11-30-2012
description:
This study sought the basis for the failure of immunosurveillance in pancreatic ductal adenocarcinoma (PDA). The FAP+ cell was shown to be immunosuppressive in a spontaneous PDA model. Bioinformatic analyses show it to be identical to the Carcinoma-associated fibroblast (CAF). FAP+ cells were sorted from pancreatic ductal adenocarcinoma. Cells were isolated in duplicate experiments and these were analysed separately. These were compared separately to previously published publicly available CD4+ T-cell subset data (C57BL/6 mice and Foxp3-RFP mice (Line 8374) GEO accession GSE20898), and previously published FAP+ cell datasets (transgenic albino (Tyr-/-) C57BL/6 mouse, GEO accession GSE39438).
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-42605
refinement:
raw
alternateIdentifiers:
42605
keywords:
functional genomics
dateModified:
01-11-2013
availability:
available
types:
gene expression
name:
Mus musculus
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-42605/E-GEOD-42605.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-42605/E-GEOD-42605.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE42605
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress
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