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Title: Long non-coding RNAs expression study of a Rett syndrome mouse model      
dateReleased:
10-03-2013
description:
In order to identify some lncRNA potentially involved in Rett syndrome we performed a mouse lncRNA expression microarray on whole brain samples coming from wild-type and MeCP2 Knock-out littermates. We found 2 lncRNAs directly bound by MeCP2 and upregulated in KO samples. We then focused on AK081227 because it overlaps with Gabrr2. The expression of this GABA receptor and the overlapping AK081227 are inversely correlated in thalamus, suggesting the long non-coding is regulating his own host. Whole brain total RNA was extracted from two Wild type mice (P60) and two MeCP2 KO littermates (P60)
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-43689
refinement:
raw
alternateIdentifiers:
43689
keywords:
functional genomics
dateModified:
05-13-2014
availability:
available
types:
gene expression
name:
Mus musculus
ID:
A-GEOD-16539
name:
Arraystar Mouse 4×44K LncRNA custom array [Agilent-027524]
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-43689/E-GEOD-43689.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-43689/E-GEOD-43689.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE43689
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress
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