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Title: Genome-wide characterization of gene regulatory mechanisms in Shh pathway underlying the pattern formation of early mouse brain      
dateReleased:
11-30-2013
description:
Shh and its receptor Ptch1 define two adjacent mutually exclusive domains: Shh+Ptch1- and Shh-Ptch1+ of E11.5 mouse brain. Gata3 ChIP-seq experiments and RNA-seq assays on Gata3-knockdown cells revealed that Gata3 up-regulates genes enriched in Shh-Ptch1+ domain. Our work is the first genome-wide characterization of gene regulatory mechanisms in Shh pathway underlying the pattern formation of early mouse brain.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MTAB-2008
refinement:
raw
keywords:
functional genomics
dateModified:
07-29-2015
availability:
available
types:
gene expression
name:
Rattus norvegicus
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-2008/E-MTAB-2008.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-2008/E-MTAB-2008.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress
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