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Title: ChIP-chip from lymph node-derived primary lymphocytes with anti-E2F2 and anti-SV40TAg      
dateReleased:
01-09-2014
description:
E2F2 is essential for the maintenance of T lymphocyte quiescence. To identify the full set of E2F2 target genes, and to gain further understanding of the role of E2F2 in transcriptional regulation, we have performed ChIP-chip analyses across the genome of lymph node-derived T lymphocytes. Here we show that during quiescence, E2F2 binds the promoters of a large number of genes involved in DNA metabolism and cell cycle regulation, concomitant with their transcriptional silencing. We performed 3 ChIP-chip experiments with an antibody against E2F2 and another 3 ChIP-chip experiments with an antibody against SV40TAg (irrelevant antibody).
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-53888
refinement:
raw
alternateIdentifiers:
53888
keywords:
functional genomics
dateModified:
05-04-2014
availability:
available
types:
gene expression
name:
Mus musculus
ID:
A-GEOD-18145
name:
NimbleGen Mouse 385K RefSeq Promoter Array [2006-06-06_MM8_RefSeq_promoter]
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-53888/E-GEOD-53888.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-53888/E-GEOD-53888.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE53888
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress
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