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Title: Transcription profiling by array of quiescent and activated rat hepatic stellate cells      
dateReleased:
05-26-2014
description:
Under conditions of the liver exposed to chronic insults such as viral infection, excess deposition of fat, regurgitation of bile acids etc., hepatic stellate cells (HSCs) change from quiescent to activated states and proliferate. During this process, HSCs secrete collagen and metalloproteinases. Involvement of collagen in sustaining activated HSC (aHSC) survival was postulated, although the precise mechanisms underlying the survival and apoptosis of aHSCs is still controversial. In this study, we compared the expression profiles between quiescent and activated HSCs to clarify the mechanisms of apoptosis for exploration of novel anti-fibrosis modalities.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MTAB-2081
refinement:
raw
keywords:
functional genomics
dateModified:
06-03-2014
creators:
Naoko K Birukawa
availability:
available
types:
gene expression
name:
Rattus norvegicus
ID:
A-MEXP-2237
name:
Agilent SurePrint G3 Rat GE 8x60K 028279 G4853A
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-2081/E-MTAB-2081.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-2081/E-MTAB-2081.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress
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