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Title: M2 cytokines alter the miRNA expression profile in macrophages      
dateReleased:
07-12-2014
description:
To examine the miRNA expression profile of the profibrogenic macrophages, we compared miRNA expression in untreated versus IL-4 or IL-13-treated macrophages using miRNA microarray.IL-4 and IL-13 treatment resulted in marked changes in 18 and 19 miRNAs in macrophages, respectively.(n=3, fold changes>2, P<0.05) Total RNA from human primary macrophages (n=3) treated with or without 20 ng/ml IL-4 or 20ng/ml IL-13 for 48 hr was isolated with a mirVana miRNA Isolation kit (Ambion, Foster, CA). The miRNA expression profile of the samples were examined using miRCURY LNA™ arrays (v18.0; covering 1921 human miRNAs, Exiqon ,Vedbaek, Denmark).
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-59348
refinement:
raw
alternateIdentifiers:
59348
keywords:
functional genomics
dateModified:
07-14-2014
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-GEOD-17107
name:
Exiqon miRCURY LNA™ microRNA Array V11.0- hsa, mmu & rno
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-59348/E-GEOD-59348.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-59348/E-GEOD-59348.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE59348
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress
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