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Title: ChIP-chip of MCF7 Sox2 regulatory region 2 transcription activity reporter unresponsive and reporter responsive breast cancer cells      
dateReleased:
09-25-2014
description:
We found that MCF7 and ZR751 Sox2-expressing breast cancer cell lines comprise of cells with heterogeneous Sox2 transcription activity reporter response. A small subset of Sox2 reporter responsive cells are more tumourigenic than the bulk Sox2 reporter unresponsive cells. We questioned whether Sox2 exhibit differential gene promoter occupancies in the two cell subsets to govern differential gene expression patterns. Sox2 ChIP in reporter unresponsive (RU) and reporter responsive (RR) cells (duplicate samples) were compared. IgG ChIP in RU and RR cells served as the negative controls.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-61703
refinement:
raw
alternateIdentifiers:
61703
keywords:
functional genomics
dateModified:
09-26-2014
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-GEOD-15802
name:
NimbleGen Human ChIP-CHIP 3 x 720k REFSEQ Promoter Array [090618_HG18_Refseq_Prom_ChIP and 100718_HG18_Refseq_Prom_ChIP]
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-61703/E-GEOD-61703.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-61703/E-GEOD-61703.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE61703
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress
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