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Title: Transcription profiling by array of mouse E10.5 TLR2+ CD11b+ embryonic phagocytes to identify several novel markers      
dateReleased:
12-01-2014
description:
The detection of Toll-like receptor 2 (TLR2) expression on E10.5 early embryonic phagocytes prompted us to determine the list of markers co-expressed with TLR2 in a cell-type specific manner. Thus, a comparative expression profiling of cDNAs between murine E10.5 TLR2+ CD11b+ embryonic cells and TLR2+ CD11b+ peritoneal macrophages as well as between TLR2+ CD11b+ and TLR2- CD11b- embryonic cells were performed using Illumina arrays. Each pairwise comparison experiment was performed in triplicate. Our data identified several novel markers of early embryonic phagocytes that could be utilized for the isolation, manipulation and functional characterization of this poorly characterized cell population. In this context, Ferroportin1 (Slc40a1) was highly expressed on E10.5 phagocytes what suggests the critical contribution of these cells to the homeostasis of iron metabolism during embryonic development.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MTAB-1537
refinement:
raw
keywords:
functional genomics
dateModified:
11-17-2014
availability:
available
types:
gene expression
name:
Mus musculus
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-1537/E-MTAB-1537.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-1537/E-MTAB-1537.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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