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Title: MicroRNA expression profile in CHME3 cells infected with Japanese encephalitis virus      
dateReleased:
01-01-2015
description:
CHME3 cells grown on six-wells were infected with Japanese encephalitis virus (JEV) (P20778 strain), and total RNA was isolated from cells at 6, 24 and 48 h of post infection. MicroRNA expression was significantly altered in JEV-infected human microglial cells. A time-dependent change in microRNA profile was noted. Bioinformatics analysis identified anti-correlation between differentially expressed miRNAs and the gene expression at different time point which ultimately affected several signalling pathways in microglia cells. Brain-enriched microRNAs and a set of microRNA previously designated as NeurimmiRs were also differentially expressed in response to JEV infection. CHME3 cells grown on 6-well plate. Three replicates of uninfected and JEV-infected samples at each time point (6, 24 and 48 h of post infection) were used for microRNA array.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-57410
refinement:
raw
alternateIdentifiers:
57410
keywords:
functional genomics
dateModified:
01-03-2015
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-GEOD-16384
name:
[miRNA-3] Affymetrix Multispecies miRNA-3 Array [miRNA-3_0] or [miRNA-3_1]
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-57410/E-GEOD-57410.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-57410/E-GEOD-57410.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE57410
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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